High blood glucose levels can have an impact on the brain's functional connectivity, which connects brain regions with similar functional qualities, as well as brain matter.
cause small-vessel disease, which restricts blood flow in the brain, causing cognitive impairments
if severe enough, contributing to the development of vascular dementia.
it penetrates the brain and binds to receptors in memory networks such as the hippocampus, hypothalamus, and insular cortex.